11 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... Complications and Treatment ... SideEffects #Table #Diagnosis ... #Pharmacology # ... Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... benefit of immediate chemotherapy ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Post-Intensive Care Syndrome (PICS)
Symptoms of PICS:
 - Physical Domain: Generalized weakness, Fatigue, Difficulty walking
 - Cognitive
Syndrome (PICS) Symptoms ... guide targeted treatments ... - Delirium ... Syndrome #PICS #diagnosis ... #management #criticalcare
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - Cytotoxic chemotherapy ... Syndrome #TLS #diagnosis ... #management #hematology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic ... #PAD #ICU #CriticalCare ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : >3 symptoms, or ... Renal Failure Treatment ... #management #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Cytotoxic drugs/Chemotherapy ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
disease, Cancer chemotherapy ... Neurological symptoms ... Medication/Drug toxicity ... epilepticus Treatment ... #management #neurology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... factor (GCSF) treatments ... ) • Intensive chemotherapy ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology