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The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
eventually leads to demyelination ... spinal column demyelination ... #Pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations: Demyelinating ... Disease, PRES Pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Acute autoimmune demyelinating ... • Resulting in demyelinating ... the underlying pathophysiology ... as either demyelinating
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Immune-mediated demyelination ... Differential #Diagnosis #Pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... polyneuropathy with demyelination
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
Sclerosis) -> Demyelination ... #constipation #pathophysiology
Demyelinating Diseases - Differential Diagnosis
 • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE
 •
Demyelinating Diseases ... Adrenoleukodystrophy #Demyelinating
CNS Ring-Enhancing Lesions - Differential Diagnosis Framework

Ring Completeness
 • Incomplete: Demyelinating Disease
 • Complete (MAGIC):
• Incomplete: Demyelinating
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
chronic inflammatory demyelinating
MAGIC DR – a handy mnemonic used to remember the potential causes of a cerebral ring
Contusion D – Demyelinating