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differential algorithm causes gitelman hypernatremia hyponatremia pathophysiology table acidosis criticalcare drugs hypertension hypomagnesemia hypomg hypotonic lactate lactic low management medications
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... , Cushing syndrome ... #Workup #Algorithm ... #nephrology #sodium
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Hypernatremia Diagnosis ... and Workup Step ... Repeat the sodium ... • nephrotic syndrome ... #Nephrology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... overdose) - Sodium ... Fanconi syndrome ... #differential #diagnosis ... #nephrology #Causes
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology ... #diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... (renal potassium ... , Renal tubular ... #diagnosis #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
- Differential Diagnosis ... (correction of hypokalemia ... Oral sodium loading ... • Cushing’s syndrome ... Causes #Screening #Workup
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Workup Blood Work ... : - Hypokalemia ... #Diagnosis #Workup ... #nephrology
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Hypotension & Hypovolemia ... Ischemia, Compartment Syndrome ... Beta-Agonists, ↑ work ... toxic alcohols, Sodium ... liver Failure, Renal
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia: • Hypovolemia ... Cirrhosis, Nephrotic Syndrome ... Differential #Algorithm #diagnosis ... #causes #nephrology ... #sodium #low
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