21 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... - APLS • Acute ... Gardner-Diamond syndrome ... #Diagnosis #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... : • Defect in fetal ... = nonspecific (nausea ... infiltration) Differential
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... - Differential ... Neoplastic / Hematologic ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... starvation - Acute ... Hypomagnesemia #Causes ... #diagnosis #differential ... medications #drugs #pharmacology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Manifestations Causes ... Findings: • Acute ... Manifestations #Differential ... beriberi #nutrition #pathophysiology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Emergencies - Differential ... Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Hyperuricemia • Acute ... emergencies #oncology #differential
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... iniury, Compartment syndrome ... Dermatomyositis) AKI - Pathophysiology ... #Summary #causes
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... TLS #diagnosis #management ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Loss of sensation distal ... - Acute rheumatic ... #differential #