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diagnosis differential hematology causes management vasculitis algorithm anterior behcet classification cll disease erythematosus fatigue lupus lymphocytic mds myelodysplasia myelodysplastic ophthalmology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... non-Hodgkin lymphoma SLL ... #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... tears, Ischemia, Leukemia ... • Arthritis: SLE ... Recurrent and chronic ... signs #symptoms #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Metabolic • Renal ... Arthritis • SLE ... Myasthenia Gravis Pharmacologic ... Fatigue Syndrome ... #Chronic #Fatigue
Causes of Anterior Uveitis - Differential Diagnosis Anterior Uveitis - 90% of cases of Uveitis • Inflammation
Immunocompromised-CMV • Chronic ... Inflammatory: Behcet's, SLE ... , TINU syndrome ... (w/ renal involvement ... : Malignancy - Leukemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... Exposure to heavy metal ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... • Mikulicz syndrome ... lubricants • Pharmacologic ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Eosinophilia, asthma, chronic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
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