10 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary ... Antinuclear (ANA ... severe disease & renal ... #rheumatology # ... management
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
will vary with clinical ... Propofol infusion syndrome ... glycol (solvent) toxicity ... No pharmacologic ... CriticalCare #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(Clinical Dx). ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... signs #symptoms #rheumatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... - Summary Clinical ... erythematosus (SLE ... /I • SAMS clinical ... myopathy #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... lubricants • Pharmacologic ... #Rheumatology # ... Diagnosis #Management
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
constellation of clinical ... renal failure ... PRIS #Diagnosis #Management ... #Pharmacology # ... Toxicity #Toxicology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
fatigue, altered mental ... acute coronary syndrome ... differential #algorithm #management ... #criticalcare #icu ... #clinical #pharmacology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
the most common clinical ... cases such as: • SLE ... Diagnosis: • Clinical ... Polychondritis #rheumatology ... #diagnosis #management