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diagnosis oncology clinical smear apl auer differentiation eosinophilia hypersegmented management mds myelodysplasia myelodysplastic promyelocytic syndrome syndromes
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
leukemia (blood ... features in most cases ... #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... in a case of acute ... myeloid leukemia ... #AML #Clinical ... #Hematology #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... -> AML: Blast crises ... Lymphadenopathy AML ... Leukemia): • Neutrophils ... #Hematology #Oncology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential ... Rhinitis - Allergic Dermatitis ... Primary: - CML ... Mastocytosis - Acute ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... febrile neutrophilic ... Differentiation #Syndrome #APML ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(hypogranular neutrophils ... transformation to AML ... blood count with differential ... progression to AML ... Syndromes #diagnosis #hematology
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