8 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANAAutoimmune ... : The ANA patterns ... lupus erythematosus ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... : - ANA 95-100% ... Diagnosis and Lupus ... #Diagnosis #autoantibodies ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Diagnosis: • ANCA-associated ... rheumatologic diseases ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis: Systemic ... lupus erythematosus ... LFT • ESR • ANA ... ) pattern: antibodies ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus Erythematosus ... Workup: - ANA ... : Chronic disease ... #table #rheumatology ... #diagnosis #management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... #AntiNXP2 #Dermatomyositis ... #diagnosis #management ... #rheumatology # ... dermatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... • Anti-NXP2 (ANA ... (ANA present 80% ... #rheumatology # ... differential #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... diseases: - 10% ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... #rheumatology #