5 results
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... ABNORMAL PT/ ... Diagnosis #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #PT #aPTT #Prolonged ... hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Seen in: • Systemic ... lupus erythematosus ... lupus erythematosus ... Hypofibrinogenemia • ↑ PT ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
anti-MPO - Seen with PTU ... Discontinuation of causal ... months to years) Systemic ... Lupus Erythematosus ... comparison #table #rheumatology