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dermatology lupus sle table agglutinin aortitis champs cold compared cryoglobulinemia cryoglobulins disease druginduced erythemas hemolytic high hyperkalemia hypertension hypocomplementemia low
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... Lupus Erythematosus ... #differential # ... hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Low serum C4 complement ... lupus erythematosus ... #types #classification ... #rheumatology #
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Diagnosis Framework ... arteritis, Cogan's Syndrome ... Arthritis (RA), Systemic ... lupus erythematosus ... #Diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... • Type-I Interferonopathies ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Diagnosis: Systemic ... differential #diagnosis ... #rheumatology # ... classification
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #rheumatology #
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... neurofibromatosis, vasculitis ... #Diagnosis #Differential ... #Causes
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... often causes arthritis ... #Differential #Diagnosis ... #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
3 Types of Cold ... Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... younger pts) Differential ... #hematology #diagnosis
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