9 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Pigmented Purpuric Dermatosis ... - GPA - EGPA ... #Diagnosis #hematology ... #rheumatology #
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated Vasculitis ... pathologically or clinically ... #differential # ... diagnosis #algorithm ... #rheumatology
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Diagnosis Algorithm ... - Irritant - Rapid ... #Eczematous #SkinRash ... #dermatology #Differential ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
, proteinuria, rapidly ... > PR3 60% • GPA ... tract, and often causes ... #rheumatology # ... classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Syndrome: • Clinical ... - GPA, EGPA, microscopic ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... , proteinuria, Rapidly ... Pauci immune GN (rapidly ... tract, and often causes ... Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... Diagnosis = clinical ... very remarkable w/differential ... diagnosis = vasculitis ... them, but urgent rheumatology