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management symptoms behcet cryoglobulins dermatologic dermpath disease gca giantcell granulomatosis lesions nonpalpable oncology palpable paraproteinemias pathology polyangiitis purpura rash syndrome
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
of Cutaneous Vasculitis ... (5%): PAN > GPA ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- GPA, EGPA, microscopic ... • IgA vasculitis ... • Vasculitis ... #rheumatology # ... vasculitis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Ig A vasculitis ... HCV, HBV Not Vasculitis ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... purpura: strong sign ... differential #diagnosis ... #rheumatology # ... classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Diagnosis: Vasculitis ... #dermatology #rash ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... MPO > PR3 60/ GPA ... Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... Manifestations: ... panuveitis, retinal vasculitis ... MCC-small vessel vasculitis ... #symptoms #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... systemic inflammatory vasculitis ... Diagnosis = clinical ... diagnosis = vasculitis ... them, but urgent rheumatology
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