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hemolytic oncology pulmonary signs symptoms abscess agglutinin aplastic arteritis behcet common cryofibrinogenemia cvid dermatologic dyspnea erythematosus extravascular gca giantcell gpa
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Pulmonary HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia • ... #diagnosis #causes
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... • AIHA: warm, cold ... Diagnosis #causes ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... #differential # ... diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Agglutinin Syndrome ... Viral Infection Clinical ... anemia • Cold ... #hematology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Diagnosis: Vasculitis ... Polyangiitis #GPA #dermatology ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... , arthritis LARGE ... differential #diagnosis ... #rheumatology # ... classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
and large-vessel ... Medium and large ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
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