Dermatitis skinrash classification differential management syndrome oncology lymphoma hematology systemic secondary apml primary rheumatology

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Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /

- Generalized Differential ... : • Lymphoma ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology

Causes of Eosinophilia - Differential Diagnosis
Bugs:
- Fungus (aspergillosis)
- Viral (HIV)
- Ectoparasites (scabies, myiasis)

Rhinitis - Allergic Dermatitis ... : - CML - Lymphomas ... - Systemic Mastocytosis ... Hypereosinophilic Syndrome ... Diagnosis #Causes #hematology

Differentiation Syndrome in APML
Epidemiology:
• Incidence: common in APL (2-48% depending on the study)
• Triggers:

Differentiation Syndrome ... febrile neutrophilic dermatosis ... initiation • Differential ... #management #hematology ... #oncology

Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

, APML, CLL Acute ... + distinctive primary ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis

Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone

Marginal Zone Lymphoma ... • Neutrophilic dermatosis ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

Vaginal dryness • Primary ... other diseases • Secondary ... Nephrogenic DI Hematologic ... #Rheumatology # ... Diagnosis #Management

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Skin Disease Classification ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... the context of primary ... Erythematosus #Diagnosis #Rheumatology

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