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hematology cll differential generalized lymphocytic mds pruritus secondary systemic cancer common cvid hemeonc hypogammaglobulinemia immunodeficiency immunology myelodysplasia primary syndromes treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... syndrome Psychiatric ... #generalized #dermatology ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #Syndromes #diagnosis ... #hematology #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... syndrome Psychiatric ... #generalized #dermatology ... #Algorithm #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... • Neutropenia, anemia ... Pure red cell aplasia ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #oncology #hematology ... #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... median age at diagnosis ... tolerate anemia ... importance of clinical ... #algorithm #hematology
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