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hematology dermatology management anemia aplastic cryoglobulins cutaneous dermatologic gpa granulomatosis immune inflammatory iris manifestations mds monoclonal nonpalpable palpable paraproteinemias polyangiitis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
associated with myelodysplastic ... syndrome • Myeloid ... manifestations #myelodysplastic ... #syndrome #differential ... #oncology #clinical
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Syndrome: • Clinical ... syndrome in 80% ... HCV infection, ... 20% Sjögren's syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myeloproliferative Disease ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... /HSP • Cryoglobulinemia ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis - Skin ... Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Hyperviscosity syndrome ... (Dermato-neuro syndrome ... ) • Gleich syndrome ... #Diagnosis #Oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Diagnosis: Vasculitis ... • Goodpasture syndrome ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... • Hypocellular myelodysplastic ... syndrome (MDS) ... #hematology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Differential Diagnosis ... Mucocutaneous lymph node syndrome ... • Behcet syndrome ... • Cogan syndrome ... #Differential #Diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... cavitating pneumonia, skin ... #Inflammatory #Syndrome
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