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algorithm generalized secondary systemic biliary cholangitis cirrhosis classification clinical cutaneous dermatologic gpa granulomatosis hepatology hodgkins leukemia management paraproteinemias pbc polyangiitis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Causes == Primary ... : • Lymphoma ... Throbocythemia • Myelodisplastic ... #generalized #dermatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... : • Lymphoma ... Throbocythemia • Myelodisplastic ... #generalized #dermatology ... #causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... associated with pruritus ... Diagnosis: Vasculitis ... Polyangiitis #GPA #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... • Heavy Chain disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... asymptomatic • Pruritus ... Jaundice (later manifestation ... Endocrinopathy, Lymphoma ... #workup #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Anemia • Pruritis ... Workup: • Full ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... sweats, bleeding • Pruritis ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
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