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rheumatology algorithm anemia cholangitis cirrhosis dermatology duct extravascular hemolysis hemolytic hepatitis injury intravascular liver nonpalpable palpable paucity pbc vasculitis workup
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... SLE) - Viral infections ... APLS • Acute Infectious ... Disease Others ... Diagnosis #hematology
Bile Duct Paucity - Differential Diagnosis • Genetic: Alagille syndrome, Trisomy 21, Williams syndrome, Peroxisomal disorders
- Differential ... Panhypopituitarism • Infections ... Graft-versus-host disease ... atresia (late finding ... #hepatology #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... but elevated as disease ... fungal, viral infections ... , IgG4 related disease ... #workup #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
cold agglutin disease ... Mycoplasma pneumoniae infection ... e.g. sickle cell disease ... spherocytosis) • Infections ... diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Venoocclusive disease ... Liver Injury: • Infectious ... Hereditary: Wilson Disease ... of cholestatic disease ... #hepatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
rheumatic diseases ... to exclude are infections ... Recurrent middle ear infections ... , recent viral infection ... #Diagnosis #Rheumatology
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