14 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Pigmented Purpuric Dermatosis ... vasculitis - GPA ... reactions • Erythema gangrenosum ... #Diagnosis #hematology ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... involvement: Anti-GBM Disease ... ANCA (C-ANCA): GPA ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
Pyoderma Gangrenosum ... vasculitis which causes ... Images #Clinical #Photo ... #Dermatology #SkinRash ... #Pyoderma #Gangrenosum
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... GPA causes disease ... resemble pyoderma gangrenosum ... reticularis Differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... PAN Pyoderma gangrenosum ... Sarcoidosis • GPA ... #skin #rashes #differential ... #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Cell Arteritis (GCA ... ) • Other Causes ... swinndong #Aortitis #Differential ... #Diagnosis #rheumatology
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
heaped up borders); differential ... cell ca, pyoderma gangrenosum ... University Infectious Diseases ... Blastomycosis #SkinRash ... #photo
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Skin Lesions - Differential ... Erosive pustular dermatosis ... Pyoderma gangrenosum ... Skin #Lesions #Differential ... #Diagnosis #Dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... lesions-interstitial keratitis ... Differential ... #diagnosis #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... • Pyoderma gangrenosum ... Paraproteinemias #Hematology ... #Monoclonal #Differential