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differential management agglutinin ana anemia antinxp2 antinxp2dm cold erythematosus hematology hemolytic lupus manifestations myelodysplastic oncology patterns sjogrens skin sle systemic
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... , Polymyositis/Dermatomyositis ... #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... presentation) • Cutaneous ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... , dermatomyositis ... Clinical Features ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... antibodies ≥ 1: ... salivary ducts Clinical ... skin (xerosis) • Cutaneous ... #Rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... in the neck Cutaneous ... had more severe disease ... #rheumatology # ... dermatology
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