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hematology causes dermatology allergy approach definitions eosinophil eosinophilia erythematosus extravascular hemolysis hemolytic hypersensitivity intravascular mouth nonpalpable oral palpable platelets purpura
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Autoimmune Hemolytic anemia ... • Ex: Systemic Lupus ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Diagnosis Algorithm ... • Contact dermatitis ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... post-splenectomy, Exercise, Allergic ... #Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... #Classification ... #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... causes are asthma, allergy ... , drug reaction, ... #Algorithm #Differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Pigmented Purpuric Dermatosis ... fever • Drug reactions ... #Diagnosis #hematology ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... #Rheumatology
Oral / Mouth Lesions and Ulcers (Adult & Elderly) - Differential Diagnosis Algorithm Teeth • GERD (Dissolves
Diagnosis Algorithm ... • Mucocele • Allergic ... Reaction Non-Ulcerating ... #Oral #Mouth #Disorders ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... disease, drug reactions ... #diagnosis #rheumatology ... #classification
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