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differential table comparison hypersensitivity patterns reactions sle vasculitis antibody antineutrophil cryoglobulinemia cryoglobulins disease druginduced laboratory pathophysiology rheumatic rheumatoid sjogrens syndrome
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... Jcortesizaguirr #ANA ... #antibodies #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies ... - Local and systemic ... , and systemic lupus ... erythematosus ... #Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... : • ANCA-associated ... • (-) ANA + (+ ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... as systemic lupus ... LFT • ESR • ANA ... #rheumatology # ... classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
lgE causes mast-cell ... Action: IgG/lgM antibodies ... reaction, Haemolytic disease ... lupus erythematosus ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types II and III ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... #types #classification ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Workup: - ANA ... Lupus Erythematosus ... Workup: - ANA ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
lupus erythematosus ... antibody (ANA) ... antibodies, which ... thus, a negative ANA ... ACE level, CXR, ANCA
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