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differential hypersensitivity patterns reactions table vasculitis antibody antineutrophil comparison cryoglobulinemia cryoglobulins disease laboratory pathophysiology rheumatic rheumatoid sjogrens sle testing vasculitides
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... Jcortesizaguirr #ANA ... #antibodies #diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies ... - Local and systemic ... , and systemic lupus ... erythematosus ... #Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... lupus erythematosus ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... as systemic lupus ... ) pattern: antibodies ... #rheumatology # ... classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
lgE causes mast-cell ... Action: IgG/lgM antibodies ... reaction, Haemolytic disease ... lupus erythematosus ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types II and III ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... #types #classification ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
lupus erythematosus ... antibody (ANA) ... antibodies, which ... thus, a negative ANA ... ACE level, CXR, ANCA
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... TYPE IV RTA, TYPE ... Arthritis Malignancy ... #Rheumatology # ... Diagnosis #Management
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