12 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Neutrophilic dermatosis ... leukocytoclastic vasculitis ... #differential # ... dermatology #oncology #clinical
Sarcoidosis - Skin Manifestations

This is a quick overview of some of the cutaneous manifestations of sarcoidosis.
of some of the cutaneous ... Sarcoid Plaques • Lupus ... Sarcoidosis #diagnosis #clinical ... treatment #photo ... #dermatology #skinrash
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary and renal manifestations ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis ... Complex: Systemic lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... Necrotizing, pauci-immune ... respiratory tracts Immune ... such as systemic lupus ... strong sign of cutaneous
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • IgA vasculitis ... small-vessel vasculitis ... • Vasculitis ... #rheumatology #vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... Strong sign of cutaneous ... - interstitial keratitis ... #Differential #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... to cold IgG • Lupus ... Hematology #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... ANCA-associated vasculitis ... context of primary immune ... • Mesenteric vasculitis ... Vasculitis: •
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
vasculitis Skin ... Diagnosis: Vasculitis ... Granulomatous vasculitis ... • Necrotising vasculitis ... leukocytoclastic vasculitis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... Manifestations: ... panuveitis, retinal vasculitis ... ) • Cutaneous Lesions ... MCC-small vessel vasculitis