13 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cause Organ Damage ... : • Clinical triad ... (e.g. systemic lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
causes arthritis ... to exclude are infections ... purpura: strong sign ... LFT • ESR • ANA ... differential #diagnosis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... of the spinal cord ... Lack of UMN/LMN signs ... , and cryoglobulins ... Muscle Biopsy: Dermatomyositis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... Leukocytoclastic vasculitis ... - Lupus - Leukemia
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... : • + Clinical ... • Negative causes ... Antiphospholipid syndrome
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... , Loose anagen syndrome ... Examination: • Signs ... DHEAS) • ANA
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... causes arthritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Still disease, dermatomyositis ... fibromyalgia) • Infections
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
matter, spinal cord ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management ... #signs #symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... causes need to ... #management #neurology ... #differential