18 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... (e.g. systemic lupus ... classification #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... : • + Clinical ... • Negative causes ... Antiphospholipid syndrome ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Pigmented Purpuric Dermatosis ... vasculitis/HSP • Cryoglobulinemia ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
causes arthritis ... to exclude are infections ... purpura: strong sign ... Serologies for Cryoglobulins ... #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... - Lupus - Leukemia
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... Capitis - Skin ... , Loose anagen syndrome ... Examination: • Signs
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... et diutinum Neurologic ... to cold IgG • Lupus ... #Monoclonal #Differential ... #Diagnosis #Oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Still disease, dermatomyositis ... fibromyalgia) • Infections
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... , neurologic, and ... causes arthritis ... + MPO) Cryoglobulinemic ... #Diagnosis #Rheumatology