6 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Agglutinin Syndrome ... Clinical Presentation ... Diagnosis: • hemolytic ... younger pts) Differential
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Neutrophilic dermatosis ... (dermatomyositis ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Palpable Rash: - Autoimmune ... Vasculitis (lupus ... immunoglobulins & cryoglobulins ... • Skin biopsy ... #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... to exclude are infections ... C-ANCA) pattern: antibodies ... Serologies for Cryoglobulins ... differential #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
associated with autoimmune ... malignancies, vasculitis ... Malignancy • Infections ... • Negative causes ... Antiphospholipid syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Differential ... Still disease, dermatomyositis ... fibromyalgia) • Infections