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diagnosis rheumatology anemia hematology hemolytic algorithm causes cord cryoglobulinemia cryoglobulins disease erythematosus extravascular hemolysis intravascular neurology sle spinal spinalcord systemic
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Cryoglobulins (Vasculitic ... Agglutinin Syndrome ... Clinical Presentation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... agglutin disease ... lymphoproliferative disorders ... disease, Copper and ... Extravascular #Causes #differential
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... : HCV infection, ... HBV infection, ... (e.g. systemic lupus ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... inflammation Others: • Lupus ... such as systemic lupus ... to exclude are infections ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections ... Clinical Features
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... neurological lesion: Clinical ... Infections: - ... Actinomyces, Blastomyces dermatitidis ... MCTD, Sjogren syndrome
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