6 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Agglutinin Disease ... Agglutinin Syndrome ... #agglutinin #disease
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... agglutin disease ... , Copper and lead ... Extravascular #Causes #differential ... #anemia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Others: • Lupus ... such as systemic lupus ... to exclude are infections ... #rheumatology # ... classification
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... due to cold IgG ... • Lupus anticoagulant ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Leukocytosis, anemia ... Coli - P. ... : • Vasculitis