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diagnosis hematology anemia causes hemolytic thrombocytopenia bleeding dermatologic dermatology erythematosus gpa granulomatosis hemolysis hemostasis management pediatrics peds polyangiitis purpura rash
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... Causes Intravascular ... hemoglobinuria (PNH) Extravascular ... agglutin disease ... #Extravascular
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Agglutinin Disease ... Agglutinin Syndrome ... the RBCs causing intravascular ... #agglutinin #disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... Others: • Lupus ... to exclude are infections ... #rheumatology # ... classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... Diagnosis: Vasculitis ... Granulomatous vasculitis ... • Necrotising vasculitis ... , extravascular
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
SLE (systemic lupus ... (disseminated intravascular ... Congenital heart disease ... other severe infections ... - Vasculitis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... ANCA-associated vasculitis ... fibromyalgia) • Infections ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... von Willebrand syndrome ... , disseminated intravascular ... integrity == • Vasculitis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- 30-40 years old ... including systemic lupus ... ANCA-associated vasculitis ... cell lymphoma - Intravascular ... diagnosis #management #rheumatology
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