4 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
- Intravascular ... vs Extravascular ... Causes Intravascular ... agglutin disease ... #Hemolytic #Intravascular
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome ... Diagnosis: • hemolytic ... • Compensated hemolysis ... the RBCs causing intravascular ... #hemolytic #anemia
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
SLE (systemic lupus ... (disseminated intravascular ... Congenital heart disease ... other severe infections ... - Vasculitis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... • Coombs (-) hemolytic ... anemia due to cold ... #Monoclonal #Differential