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hematology anemia management cold cryoglobulinemia cryoglobulins erythematosus extravascular hemolysis hodgkins intravascular monoclonal paraproteinemias pediatrics peds polychondritis purpura relapsing systemic thrombocytopenia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
pallor, dyspnea, and ... Diagnosis: • hemolytic ... testing for anti-C3d and ... hemoglobinemia and ... #disease #hemolytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
, CLL, lymphoma, ... . primary cold agglutin ... , Copper and lead ... #differential # ... diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology # ... classification
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
(systemic lupus ... Congenital heart disease ... Meningococcal and ... - Vasculitis ... #differential #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
temperatures below 37°C and ... endothelial injury and ... : • Clinical triad ... ) • Types II and ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Amyloidosis and ... histiocytosis, and ... to cold IgG • Lupus ... @KirtanPatolia and ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... - Clinical Presentation ... nodosum • Immune hemolytic ... #diagnosis #classification ... #hematology #oncology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
frequently: 40 and ... pain, tenderness, and ... night sweats, and ... as: • SLE • RA ... • Lymphoma •
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