13 results
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... drugs, malignomas, and ... infectious diseases ... - systemic lupus ... #Diagnosis #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Syndrome (CAS): ... Clinical Presentation ... younger pts) Differential ... #anemia #hematology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
(LCV) of the Hand ... Differential for ... Churg-Strauss syndrome ... #LCV #Hand #skinrash ... #dermatology #clinical
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Pigmented Purpuric Dermatosis ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology #
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... arteritis, Cogan's Syndrome ... (RA), Systemic lupus ... MD @MithuRheu and ... #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Others: • Lupus ... such as systemic lupus ... to exclude are infections ... #rheumatology # ... classification
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... . primary cold agglutin ... , Copper and lead ... Extravascular #Causes #differential ... #diagnosis #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... : HCV infection, ... • Autoimmune diseases ... (e.g. systemic lupus ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: ... permanent alopecia Differential ... fibromyalgia) • Infections ... Erythematosus #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... SLE), Sjogren's Syndrome ... Lymphoproliferative Disorders, Infection ... ANA #patterns #rheumatology ... #diagnosis #differential