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ana antinuclear classification differential systemic vasculitis activation antibodies autoantibodies comparison cryoglobulinemia cryoglobulins hematology macrophage polychondritis relapsing types vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... : The ANA patterns ... : Lupus (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... : • ANCA-associated ... Clinical Features ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Erythematosus ( ... : Chronic disease ... #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
is clinically suspected ... overlap syndromes ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... ) pattern: antibodies ... ) pattern: is usually ... vasculitis, and SLE ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... (e.g. systemic lupus ... erythematosus (
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... : • SLE • RA - ... : • Clinical tests ... Polychondritis #rheumatology ... #diagnosis #management
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