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classification ana antibody antineutrophil antinuclear cryoglobulinemia differential erythematosus polychondritis relapsing systemic types
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... • Sjögren syndrome ... Vasculitis: • ... Renal-limited vasculitis ... #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... #vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... often causes arthritis ... Vasculitis: + MPO-ANCA ... , and SLE) • Urinalysis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... syndrome, and mixed ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... #Syndrome #Rheumatology ... #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
as: • SLE • RA ... Most common • Sjogren ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology ... #diagnosis #management
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