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diagnosis causes rheumatology classification lung table algorithm dermatology eosinophilia hypersensitivity ild neurology reactions types vasculitis abscess ana antibodies antinuclear associations
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... , Contact Dermatitis
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... PSS: Sjogren syndrome ... : systemic lupus ... connective tissue disease
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
histiocytosis • Allergic ... AI: EGPA, IgG-4 disease ... , Behcet disease ... Chronic inflammatory disease ... Diagnosis #Algorithm #allergy
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... a.k.a. extrinsic allergic ... Connective Tissue Disease ... connective tissue disease ... Interstitial #Lung #Diseases
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... rheumatology #diagnosis #differential
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... Complex: Systemic lupus ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... reaction, Haemolytic disease ... Examples: Contact dermatitis ... reactions #types #allergy ... classification #comparison
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Eosinophilic Lung Diseases ... loss, malaise • Allergic ... Eosinophilic #Lung #Diseases ... #pulmonary #differential ... #diagnosis #comparison
Headache Etiologies and Associated Spectrum of Severity of Disease by System Critical, Emergent and Non-Emergent Causes CNS, neurologic,
of Severity of Disease ... Collagen vascular disease ... Musculoskeletal Allergy ... Infectious disease ... Pulmonary or oxygen
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... pain • Kawasaki Disease ... (Granulomatous disease ... atherosclerotic disease ... most important diseases
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