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classification hypersensitivity reactions bradykinin champs complement cryoglobulins definitions dermatology differential foot hematology hypocomplementemia immunology low management mediated mnemonic moccasin pathophysiology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Erythematosus,
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... , and systemic lupus ... erythematosus ... Pathophysiology #Allergy
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... , hereditary angioedema ... S - Systemic Lupus ... Erythematosus (
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... (e.g. systemic lupus ... erythematosus ( ... #rheumatology #
Bradykinin-mediated Angioedema Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Clinical features ... abdominal pain Types ... MGUS), autoimmune disease ... (lupus) • Iatrogenic ... #allergy #immunology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Diagnosis? ... sp. pruritic, erythematous ... dyshidrotic, atopic, or allergic ... eczematous dermatitis ... #clinical #photo
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