6 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... Post-streptococcal glomerulonephritis ... , and systemic lupus ... - Contact dermatitis ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reaction, Haemolytic disease ... Post-streptococcal glomerulonephritis ... , Systemic lupus ... Examples: Contact dermatitis ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... IgA nephropathy, lupus ... autoAb against type ... #Differential # ... Diagnosis #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Renal Syndrome Definition ... alveolar hemorrhage + Glomerulonephritis ... symptomatology Differential ... Complex: Systemic lupus ... #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... inflammation Others: • Lupus ... Differential ... such as systemic lupus ... #rheumatology #classification