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diagnosis differential nephritis rheumatology treatment druginduced kidneyinjury medications membranous pulmonary syndrome vasculitis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis ... ANCA-negative vasculitis ... Complex: Systemic lupus ... sclerosis • Anti-Glomerular ... differential #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... - Skin, glomeruli ... such as systemic lupus ... • Urinalysis (Renal ... #rheumatology #classification
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... or 0.5 g/day → renal ... by 12 months Classification ... Focal LN (<50% of glomeruli ... #rheumatology #nephrology
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Injury • Pre-Renal ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA ... #nephrology #Medications
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... for worsening disease ... #Treatment #management ... #nephrology
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