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rheumatology vasculitis activation alopecia ana antibodies antinuclear classification cll hair hairloss leukemia loss lymphocytic macrophage management manifestations mas monoclonal myelodysplastic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic ... diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... lupus erythematosus ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Neutrophilic dermatosis ... dermatomyositis, SLE ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Diagnosis Framework ... , Loose anagen syndrome ... Vitamin D levels Systemic ... weight loss • Chronic ... #Diagnosis #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... lupus erythematosus ... [SLE], AOSD) • ... with leukopenia, anemia ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... Diagnosis: Systemic ... lupus erythematosus ... vasculitis, and SLE ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... Eosinophilia, asthma, chronic ... #Diagnosis #Rheumatology
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