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differential management antinxp2 classification clinical comparison dermatomyositis druginduced monoclonal myelodysplastic paraproteinemias syndrome systemic vasculitides
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #dermatology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... lupus erythematosus ... • Anti-Ro/SSA autoantibodies ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Erythematosus ( ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... ) Autoantibodies ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... such as systemic lupus ... erythematosus, ... , and SLE) • Urinalysis ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... in the neck Cutaneous ... had more severe disease ... #rheumatology # ... dermatology
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