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differential classification erythematosus signs symptoms systemic behcet cryoglobulinemia management oncology pain paraproteinemias rashes types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... ) • Cutaneous ... (e.g. systemic lupus ... classification #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... such as systemic lupus ... , and SLE) • Urinalysis ... Serologies for Cryoglobulins ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... , Purpura, Urticaria ... #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... Clinical Features ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... vesicular eruption • Joints ... , joint & gut involvement ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
) • Cutaneous Lesions ... lesions, palpable purpura ... (Clinical Dx). ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology
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