7 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... antibodies bind to mast ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... #CNS #neurology ... cerebritis #diagnosis #management ... #treatment
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes mast-cell ... to complement activation ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... Examples: Contact dermatitis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... erythematosus [SLE ... • Drug-induced hypersensitivity ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the Treatment ... of Membranous Lupus ... treat non-renal SLE ... for worsening disease ... #management #nephrology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Evaluate for NMO, SLE ... Disorders: - SLE ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
conjunctivitis, keratitis ... : • SLE • RA - ... Sarcoidosis • Behcet disease ... affected tissue Treatment ... rheumatology #diagnosis #management