5 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... during hemolytic disease ... lupus erythematosus ... - Contact dermatitis ... Classification #Pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Cerebrovascular Disease ... , PRES Pathophysiology ... #Lupus #Erythematosus ... #SLE #CNS #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... to complement activation ... reaction, Haemolytic disease ... glomerulonephritis, Systemic ... lupus erythematosus
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management