8 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Shrinking lung syndrome ... • May involve PNS ... and CNS • Headache ... Chronic B-cell activation
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... #CNS #neurology ... cerebritis #diagnosis #management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the Treatment ... of Membranous Lupus ... for worsening disease ... #Treatment #management ... #nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... erythematosus [SLE ... • Drug-induced hypersensitivity ... Treatment: • Corticosteroids ... #Management #Hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... • 8%-27% for CNS ... • Interstitial nephritis ... Adenocarcinoma Treatment ... Rheumatology #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... that results in CNS ... Disorders: - SLE ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... pleural effusions, CNS ... granulomatous nephritis ... Differential #Diagnosis #Management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... histopathologic changes in LNs ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management