5 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus ( ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #management #treatment
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... during hemolytic disease ... , and systemic lupus ... erythematosus ... - Contact dermatitis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... highly inflammatory disease ... • Kawasaki disease ... of underlying disease ... #Macrophage #Activation
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... to complement activation ... reaction, Haemolytic disease ... erythematosus Type ... T-cells recruit macrophages
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Systemic rheumatic diseases ... , such as SLE, atherosclerotic ... disease, drug reactions ... most important diseases ... (GRANULOMATOUS DISEASE