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diagnosis ana antibody antineutrophil behcet classification erythematosus hematology inflammatory monoclonal myelitis oncology paraproteinemias patterns signs sjogrens symptoms syndromes tafro thrombocytopenia
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... connective tissue disease ... Vasculitis: • ... Renal-limited vasculitis ... diseases
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... • +ANA can be seen ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #Antibodies #ANA
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
and less common diseases ... • Systemic lupus ... polychondritis • Behcet disease ... vasculitides • ... #Syndromes #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... most important diseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such ... disease, drug reactions ... most important diseases ... (GRANULOMATOUS DISEASE
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... Sneddon-Wilkinson disease
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... disease, myelopathy ... ) • Cutaneous vasculitis ... Vasculitis: •
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... , small-vessel vasculitis ... panuveitis, retinal vasculitis ... skin injury) • Neurologic ... MCC-small vessel vasculitis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
multicentric Castleman disease ... s syndrome, ANCA-associated ... vasculitis - Infectious ... infection, rickettsial disease ... , Lyme disease,
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