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rheumatology classification differential syndrome allergy antibodies erythematosus hypersensitivity patterns reactions vasculitis allergic cryoglobulinemia cryoglobulins dermatology imdamnsharp laboratory management mnemonic oncology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... (SLE), Systemic ... @AnnKumfer #Antinuclear ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Systemic ... : Lupus (SLE), Systemic ... @AnnKumfer #Antinuclear ... #rheumatology #diagnosis
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... Antibody (ANA) ... R Renal Disease ... #IMDAMNSHARP #sle ... #systemic #lupus
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Gravis, Graves' Disease ... complexes • Ex: Systemic ... Lupus Erythematosus ... , Reactive Arthritis ... #Definitions
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... Pathophysiology #Allergy #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... • Type-I Interferonopathies ... #Systemic #Lupus ... Erythematosus #Diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Renal Syndrome Definition ... lupus erythematosus ... , Rheumatoid arthritis ... , anti-GBM ab, ANA ... #nephrology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... arthritis) • ... Types II and III ... lupus erythematosus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... (SLE) - Antinuclear ... Tests for All Types ... (to support a diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... disease. ... such as certain types ... ’s syndrome - Lupus ... Sweet #Syndrome #diagnosis
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