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differential classification vasculitis ana antibodies antinuclear joint laboratory pain patterns table allergy aortitis approach comparison cryoglobulins dermatology disease druginduced factor
Approach to a Positive (+) Rheumatoid Factor (RF) (+) RF does not always = RA Rheumatic disorders: •
arthritis • SLE ... connective tissue (types ... III) • Mixed cryoglobulinemia ... #Factor #RF #rheumatology ... #differential #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid ... #rheumatology #
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
and Associated Rheumatic ... erythematosus ( ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology ... #diagnosis #differential
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Disease (IgG4-RD), Rheumatoid ... Systemic lupus ... erythematosus (SLE ... #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
rheumaticum • Rheumatic ... lesions • Discoid lupus ... erythematosus ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus ( ... erythematosus ( ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... ANCA-associated vasculitis, rheumatoid ... Kikuchi disease • Type-I ... #Diagnosis #Rheumatology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
glomerulonephritis, rheumatoid ... arthritis, and ... systemic lupus erythematosus ... - Contact dermatitis ... Pathophysiology #Allergy #Diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Behcet disease, Cryoglobulinemia ... Complex: Systemic lupus ... erythematosus, ... Rheumatoid arthritis ... #nephrology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... Erythematosus ( ... #table #rheumatology ... #diagnosis #management
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