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differential classification vasculitis champs complement cryoglobulins glomerular hematology hypocomplementemia low mnemonic nephritic nephrotic pulmonary renal rpgn syndrome vasculitides workup
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... , type 1 (50%-80% ... S - Systemic Lupus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... autoAb against type ... #Differential #Diagnosis ... #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... Behcet disease, Cryoglobulinemia ... Complex: Systemic lupus ... Disease-specific testing ... #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... inflammation Others: • Lupus ... such as systemic lupus ... #rheumatology #
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
factor - Screen for cryoglobulinemias ... (types 2 and 3) ... #workup #diagnosis ... #glomerulonephritis ... nephrotic #nephritic #nephrology
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